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$895,000
688278178 MLS
Discover the untapped commercial and recreational potential of this unique multi-use property just minutes from the Oregon Dunes. Privately situated in a secluded setting with secured gated access and a looping driveway, this property offers outstanding flexibility for business owners, investors, and outdoor enthusiasts seeking space to develop, operate, or simply enjoy.The oversized main shop, complete with its own restroom, is a versatile commercial-grade asset ready to support a wide range of uses — contractor operations, equipment storage, workshop space, hobby business, light industrial, or recreational hub. Below, a second garage with 2 garage doors for more functional square footage, expanding the property's capacity for multi-tenant use, fleet storage, or separate business operations. Together, the dual structures, on-site amenities, and open layout create a rare opportunity to customize the property to fit virtually any commercial or personal vision.For those exploring alternative uses, the property's open space, dual shop/garage configuration, and access layout invite creative possibilities — from additional storage operations and small business uses to recreational camping sites, a private retreat, or other adaptive concepts. Buyers are encouraged to perform their own due diligence to explore which of these opportunities best align with their goals. All uses, zoning classifications, permitted development, camping allowances, and any county-level approvals must be independently verified by the buyer with the appropriate county planning and zoning authorities.Its prime coastal proximity, room to store play toys and recreational vehicles securely behind the gate, and peace of mind offered by the private, secure setting make it an ideal candidate for buyers looking to blend commercial utility with lifestyle or leisure potential.Whether your goal is an investment property, a base of operations, or a flexible coastal retreat, this is a rare opportunity.

85340 HIGHWAY 101, Florence

Listing courtesy of TR Hunter Real Estate.

$125,000
767741951 MLS
BUSINESS OPPORTUNITY, THE JOLLY EGRET! Don't miss your chance to own a business in the heart of Florence! Ideally located on the main strip of Old Town, this business offers excellent visibility and storefront appeal. The sale includes all fixtures and retail, making it a true turnkey opportunity. Inside, you'll find a welcoming retail space, private office, convenient storage area, and bathroom; everything you need to step right in and start running your business. This business opportuity does not include the building, just the business and inventory. Conveniently located in an area of tourist traffic, local favorites and much more, this prime location offers the perfect foundation for your next venture!

1308 BAY ST, Florence

Listing courtesy of TR Hunter Real Estate.

$1,295,000
168796801 MLS
Now is your chance to own your own piece of Oregon History. The former Cushman Store Boat & Tackle with Marina, includes an RV Park with 7 full hookups, and incredible river frontage with deep water access. The main building is now a 3-bedroom 2-bathroom residence, for someone to live and work in the same building and bring this place back to prominence. Located just east of Florence, ideal for a convenience store and RV Park business to offer a wonderful location for fishing and sporting along the Siuslaw River. The Marina Features Commercial Grade Concrete docks extending 120 feet for plenty of space for moorage of all sizes. Motivated seller, work with your agent and bring your vision and offers

6750 HIGHWAY 126, Florence

Listing courtesy of eXp Realty, LLC.

$280,000
764501795 MLS
Positioned in a prime, high-visibility corridor along Highway 101 in the center of Florence, this property offers exceptional exposure, convenient access, and close proximity to established businesses and nearby residential areas. The location naturally supports consistent foot traffic while remaining easily accessible for drivers, making it well-suited for a variety of commercial applications. Inside, the building offers a versatile and efficient layout designed to accommodate a wide range of business uses. The open floor plan allows for easy customization, whether you envision professional office space, retail, restaurant use, medical or wellness services, or a mixed-use concept. The main level includes approximately 3,174 square feet of space. The upper level presents a blank slate, ideal for creating a residential unit, additional office suites, or a combination of both. With its own exterior entrance and pre-installed plumbing and electrical stub-ins, the second floor is ready to be transformed to meet your specific needs. Recent improvements add value and peace of mind, including a newer membrane roof, a fully cleared and prepped upper level, and significant upgrades to the electrical panel. Designed with both functionality and long-term performance in mind, the property offers strong potential for stable occupancy and income generation. Flexible space configurations allow owners to tailor leasing strategies or adapt to changing market demands, maximizing return on investment. This is an opportunity to acquire a well-located asset with both immediate income potential and long-term appreciation upside. Additionally, this property can be purchased as part of a package with the neighboring 478 Hwy 101 location, creating even greater investment potential.Opportunities like this are becoming increasingly rare

470 HIGHWAY 101, Florence

Listing courtesy of Hybrid Real Estate.

$1,100,000
732672596 MLS
An excellant investment and business opportunity on a prime commercial property on Highway 101 with very high traffic count at your front door. Great accessibility to this prime half acre with a 4300 square feet retail and commercial building, a huge paved parking lot with 22 designated spaces and a large 1000 gallon propane storage tank. The front 2200 square feet of retail space has been recently updated with new windows and premium laminate flooring. This space is leased at $2,800/month with a recent 10 year lease with escalation clauses. The rear portion of the building features a state-of-the-art laundromat with 18 Dexter washers and 10 double stacked dryers,(20) ranging from 20 to 90 pound capacities, all with recent upgrades to digital card readers. The laundry is ADA accessible with three card access showers and restroom. There is a room setup for an attendant to provide "Fluff and Fold" service with the potential of 25/30% revenue increase. There is a twelve camera "Ring" security system with full remote control to open and close access.

2420 HIGHWAY 101, Florence

Listing courtesy of All State Real Estate.

$985,000
128087303 MLS
Rare offering - spacious, well maintained professional office building in the heart of Florence. Formerly a real estate office, the flexible and innovative design would accommodate a wide variety of uses, including work-share or flex space. With the 2nd reception area, even 2 major businesses could share the building, 23 individual offices in total: conference rooms, multiple restrooms, breakroom and storage. Well maintained since built in 1991, the exterior was recently painted in 2025, a new roof installed in 2019, and parking lot was sealed and striped in 2024. Lots of parking front and rear, with 130' of U.S. Hwy 101 frontage and prime visibility. Owner will finance with excellent terms or even consider a lease. Call for more details.

1875 HIGHWAY 101, Florence

Listing courtesy of Coldwell Banker Coast Real Est.

$565,000
525250622 MLS
Strategically situated in a high-traffic area along Highway 101 in the heart of Florence, this building benefits from outstanding exposure, easy accessibility, and proximity to established businesses, and residential neighborhoods. The location supports both steady foot traffic and convenient vehicular access, making it ideal for a wide range of commercial uses. Inside, the building features a functional and adaptable interior that can accommodate virtually any commercial vision. The open design allows for seamless customization, whether for professional offices, retail operations, restaurant, medical or wellness services, or mixed-use concepts The first floor offers 3637 sq feet of retail space, an accessible bathroom, office and breakroom space the possibilities are endless. Upstairs is a blank canvas with space for up to four apartments, additional offices or a combination. With exterior access to the second floor and wiring and plumbing stubbed in, there is no limit on what it can be used for! Current upgrades to the property include a newer membrane roof, full gutting and clean up of the upper level, extensive electrical panel upgrades, security system, and more! From an investment perspective, this property represents a compelling rate-of-return opportunity. Designed to support stable occupancy and long-term value growth, the building offers a layout conducive to attracting quality tenants across multiple industries. The income potential is enhanced by flexible configurations, allowing owners to optimize leasing strategies or adapt spaces to evolving market demands. Investors will recognize the advantage of acquiring a well-positioned asset with both immediate revenue possibilities and future appreciation prospects. This can also be bought as a package deal with neighboring 470 Hwy 101! Opportunities like this are increasingly difficult to find — a commercial property that checks the boxes for location, income performance and expandability.

478 HIGHWAY 101, Florence

Listing courtesy of Hybrid Real Estate.

$1,900,000
639008570 MLS
Prime commercial opportunity on a high-visibility corner location! This 0.51-acre commercial property spans three tax lots and sits at the corner of Hwy 101 and 37th Street, offering approximately 120 feet of Hwy 101 frontage for excellent exposure. The property features two income-producing buildings. The first is a charming two-story building built in 1938. The upper level offers a 720 sq ft, 1-bedroom, 1-bathroom apartment—ideal for owner occupancy or rental income. The main level consists of 2,128 sq ft and is currently operating as a thrift store. The second building, constructed in 1991, is a single-level commercial structure with versatile use. Approximately half of the building (1,696 sq ft) is currently operating as a laundromat, while the remaining 1,504 sq ft is home to a deli/café. Exceptional visibility, multiple revenue streams, and flexible commercial use make this a standout investment along Hwy 101.

1856 37TH ST, Florence

Listing courtesy of West Coast Real Estate Service.

$565,000
24089891 MLS
Seller will consider owner carried financing! Outstanding Commercial Opportunity in the Heart of Florence!Don't miss this rare chance to own a spacious and versatile commercial property in a prime central location. Situated just off Highway 101 in the thriving heart of Florence, this 3,457 sq ft building offers exceptional potential for investors, business owners, or medical professionals seeking a turnkey space.The property boasts ample on-site parking and excellent street visibility, making it ideal for high-traffic business use. Currently configured as office space, the building was originally constructed and operated as a medical clinic for many years. The existing floor plan remains unchanged from its original design, allowing for a seamless transition back to medical use if desired—with minimal renovation needed.Inside, the building offers a functional layout that includes multiple private offices or exam rooms, reception and waiting areas, ADA-accessible restrooms, and ample storage. Whether you're envisioning a healthcare practice, professional office, wellness center, or other commercial venture, this property offers the space and flexibility to bring your vision to life.Located within minutes of local hospitals, shopping centers, and residential neighborhoods, this property is perfectly positioned to serve the growing Florence community. Properties like this don’t come along often—schedule your private tour today and explore the possibilities!

1576 12TH ST, Florence

Listing courtesy of Coldwell Banker Coast Real Est.

$950,000
24223879 MLS
Amazing commercial opportunity with Highway 101 frontage! This newer built commercial building sits on 0.69 acres with 4000sqft. Perfect to start or move your dream business! This building includes 3 full bathrooms, ADA compliant. 4 potential office spaces, a kitchen/break area, and a roll up door leading into a massive storage/work area, perfect for large vehicles and equipment. Additional 1800 sqft on 2nd floor is built with I-beam subfloor system that can potentially be built out. There is a 50A wall receptacle, hot and cold water bibs, and sewer drain in the shop. Also, floor drains in the bathrooms, shop, utility room, and a water treatment system installed. Lots of parking for this building. There is a concrete walkway that goes all around the building. This building is perfect for your dream business!

5129 N LOFTUS RD, Florence

Listing courtesy of TR Hunter Real Estate.

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The data relating to real estate for sale on this web site comes in part from the Internet Data Display (IDX) of the Southern Oregon Multiple Listing Service. Real estate listings held by brokerage firms other than our company are marked with the IDX logo and detailed information about them includes the name of the listing brokers. The information being provided is for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. All information subject to change and should be independently verified. Last updated: